Home > Terms > English, UK (UE) > pethidine
pethidine
Pethidine is indicated for the treatment of moderate to severe pain, and is delivered as a hydrochloride salt in tablets, as a syrup, or by intramuscular, subcutaneous or intravenous injection. For much of the 20th century, pethidine was the opioid of choice for many physicians; in 1975 60% of doctors prescribed it for acute pain and 22% for chronic severe pain. Compared with morphine, pethidine was thought to be safer, carry a lower risk of addiction and to be superior in treating the pain associated with biliary spasm or renal colic due to its putative anticholinergic effects. It was later discovered that these were all myths and that it carried an at least equal risk of addiction, possessed no advantageous effects on biliary spasm or renal colic compared to other opioids and that, due to its toxic metabolite, norpethidine, it was more toxic than other opioids, especially during long-term use.
- Part of Speech: noun
- Synonym(s):
- Blossary: Illegal Drugs
- Industry/Domain: Law enforcement
- Category: Drug trafficking
- Company:
- Product:
- Acronym-Abbreviation:
Other Languages:
Member comments
Terms in the News
Featured Terms
Maserati GranTurismo
Manufactured by Italian car company Maserati, the Maserati Gran Turismo is a two-door coupe sports car. The first model came out in 2007, following ...
Contributor
Featured blossaries
Silentchapel
0
Terms
95
Blossaries
10
Followers
Eastern Christian Ranks
Browers Terms By Category
- Electricity(962)
- Gas(53)
- Sewage(2)
Utilities(1017) Terms
- Alcohol & Hydroxybenzene & Ether(29)
- Pigments(13)
- Organic acids(4)
- Intermediates(1)
Organic chemicals(47) Terms
- Legal documentation(5)
- Technical publications(1)
- Marketing documentation(1)
Documentation(7) Terms
- Physical geography(2496)
- Geography(671)
- Cities & towns(554)
- Countries & Territories(515)
- Capitals(283)
- Human geography(103)
Geography(4630) Terms
- Social media(480)
- Internet(195)
- Search engines(29)
- Online games(22)
- Ecommerce(21)
- SEO(8)